By Robert Preidt
FRIDAY, Dec. 18, 2020 (HealthDay Information) — COVID-19 is much extra dangerous and lethal than the seasonal flu, new research affirm.
Researchers analyzed U.S. Division of Veterans Affairs information on greater than 3,600 sufferers hospitalized with COVID-19 between Feb. 1 and June 17 of this yr, and greater than 12,600 hospitalized with the flu between Jan. 1, 2017 and Dec. 31, 2019. The common age of sufferers in each teams was 69.
The dying price amongst COVID-19 sufferers was 18.5%, whereas it was 5.3% for these with the flu. These with COVID had been practically 5 instances extra prone to die than flu sufferers, in accordance with the research revealed on-line Dec. 15 within the BMJ.
COVID-19 sufferers with the very best danger of dying included these aged 75 and older who additionally had continual kidney disease or dementia, and Blacks who had been obese, or who had diabetes or kidney illness.
The research additionally discovered that COVID-19 sufferers had been 4 instances extra prone to require respiratory machines, practically 2.5 instances extra prone to be admitted to intensive care, and stayed within the hospital a mean of three days longer than flu sufferers.
A separate research from France, revealed on-line Dec. 17 in The Lancet Respiratory Drugs journal, arrived at related conclusions: Almost twice as many individuals had been admitted to the hospital for COVID-19 on the peak of the pandemic than had been for influenza on the peak of the 2018/2019 flu season. And the dying price was virtually thrice larger.
The French crew, led by Dr. Pascale Tubert-Bitter, analysis director at L’Institut Nationwide de la Santé et de la Recherche Médicale (Inserm), and Catherine Quantin, from the College Hospital of Dijon and Inserm, in contrast information from COVID-19 sufferers admitted to the hospital over a two-month interval in spring 2020 with influenza sufferers admitted over a three-month interval in the course of the seasonal flu outbreak of 2018/2019.
“The discovering that the COVID-19 dying price was thrice larger than for seasonal influenza is especially placing when reminded that the 2018/2019 flu season had been the worst prior to now 5 years in France when it comes to variety of deaths,” Quantin famous in a Lancet information launch.
Tubert-Bitter added, “Taken collectively, our findings clearly point out that COVID-19 is way more critical than seasonal influenza. At a time when no remedy has been proven to be efficient at stopping extreme illness in COVID-19 sufferers, this research highlights the significance of all measures of bodily prevention and underlines the significance of efficient vaccines.”
U.S. researchers stated a giant shock of their research was that COVID-19 sufferers had the next danger of creating diabetes, with 9 extra instances per 100 than flu sufferers.
“These sufferers did not have diabetes till they acquired COVID-19,” stated research senior creator Dr. Ziyad Al-Aly, an assistant professor of drugs at Washington College in St. Louis. “Then their blood sugar spiked, they usually wanted large doses of insulin. Is the diabetes reversible, or will it require long-term administration? Will it’s sort 1 or type 2 diabetes? We simply do not know as a result of COVID-19 barely existed a yr in the past.”
One other discovering was that COVID-19 sufferers had the next danger of acute kidney harm and extreme sepsis shock. For each issues, there have been a mean of 6extra instances per 100 COVID-19 sufferers than amongst flu sufferers.
Additionally, COVID-19 sufferers had been extra prone to want medicines to deal with severely low blood strain, a situation that may result in organ harm and dying. The speed was 11.5 extra instances per 100 sufferers than amongst flu sufferers.
“Many high-profile, public comparisons between COVID-19 and the flu have been made; nonetheless, these comparisons largely had been drawn utilizing disparate information and statistical strategies which have resulted in numerous conjecture. Our analysis represents an apples-to-apples comparability between the 2 illnesses,” Al-Aly stated in a college information launch.
“A deeper understanding of the well being dangers of COVID-19 helps to anticipate demand for well being care providers and to undertaking mortality with higher accuracy,” he added.
“We all know so little about COVID-19 due to its newness,” Al-Aly famous. “I am undecided why Black sufferers undergo and die extra. My hunch is that the trigger pertains to racial disparities in well being care, however there could possibly be different elements that we do not but know.”
The U.S. Facilities for Illness Management and Prevention has extra on COVID-19.
SOURCES: Washington College in St. Louis, information launch, Dec. 15, 2020; The Lancet Respiratory Drugs, information launch, Dec. 17, 2020